Antibiotic Susceptibility of Bacterial Strains causing Asymptomatic Bacteriuria in Pregnancy: A Cross- Sectional Study in Harare, Zimbabwe
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چکیده
Asymptomatic bacteriuria (ASB), a type of urinary tract infection (UTI), is one of common infections in pregnancy requiring antibiotic treatment. ASB is defined as growth of more than 100 000 colony forming units per millilitre (cfu/ ml) in culture of midstream urine obtained from an individual without signs and symptoms of asymptomatic bacteriuria [1,2]. ASB prevalence generally ranges from 2% to 10% [3]. Anatomic and physiological changes occurring during pregnancy increase the risk of ASB [4]. When ASB is untreated in pregnancy it often progresses later in pregnancy to pyelonephritis, an acute (UTI) [5]. Pyelonephritis is symptomatic bacteriuria associated with several pregnancy complications and adverse birth outcomes including preeclampsia, preterm birth, low birth weight and neonatal death [6,7]. Up to 40% of pregnant women develop a symptomatic UTI later in pregnancy if ASB is undetected and untreated [3,8,5]. Screening and treatment of ASB during pregnancy is an important intervention to be implemented at primary care level [9]. Treatment of ASB in pregnancy using effective antibacterial treatment decreases risk of acute urinary tract infection from 40% to 1 to 4% [3-10]. All complications of ASB during pregnancy are reduced by antibiotic therapy [9]. Several international and national guidelines recommend screening and treatment of ASB to reduce risk of pyelonephritis [6]. Several antibiotics are available for selection for treatment of ASB in pregnancy including, amoxil, ampicillin, cephasporin, nitrofurantoin, trimethoprim and sulfamethoxazole [2]. Treatment of ASB with antibiotics in pregnancy aims to clear the infection, which is only possible if the isolated bacterium is susceptible to it [6]. Selection of antibiotic to treat ASB need to be based on antibiotic susceptibility results [9]. Susceptibility test informs on effectiveness of antibiotics against infectious organisms and degree of bacterial resistance pattern [11]. The test results help to guide clinicians on appropriate selection of effective antibiotics for pathogenic strain and to prevent prescribing and administration of resistant and ineffective antibiotics [11,12]. Results of the test are often categorized Volume 6 Issue 1 2018
منابع مشابه
Antibiotic Susceptibility of Bacterial Strains causing Asymptomatic Bacteriuria in Pregnancy: A Cross- Sectional Study in Harare, Zimbabwe
Asymptomatic bacteriuria (ASB), a type of urinary tract infection (UTI), is one of common infections in pregnancy requiring antibiotic treatment. ASB is defined as growth of more than 100 000 colony forming units per millilitre (cfu/ ml) in culture of midstream urine obtained from an individual without signs and symptoms of asymptomatic bacteriuria [1,2]. ASB prevalence generally ranges from 2%...
متن کاملAntibiotic Susceptibility of Bacterial Strains causing Asymptomatic Bacteriuria in Pregnancy: A Cross- Sectional Study in Harare, Zimbabwe
Asymptomatic bacteriuria (ASB), a type of urinary tract infection (UTI), is one of common infections in pregnancy requiring antibiotic treatment. ASB is defined as growth of more than 100 000 colony forming units per millilitre (cfu/ ml) in culture of midstream urine obtained from an individual without signs and symptoms of asymptomatic bacteriuria [1,2]. ASB prevalence generally ranges from 2%...
متن کاملAsymptomatic Urinary Tract Infection in Pregnant Women
Background and Objectives: Urinary tract infection is one of the most common bacterial infections in the human population, and more frequent infection during pregnancy. With notice to this point that most of urinary tract infections during pregnancy are asymptomatic, they could lead to serious complications such as prematurity, low-birth weight, hypertension, and higher fetal mortality rates...
متن کاملStudy of Asymptomatic bacteriuria in pregnant women and antibiotic _ sensitivity of isolated bacteria in Tabriz 1996
Urinary tract infection ( UTI) is a common disease , which may occur as Asymptomatic in both sexes at any age. Asymptomatic bacteriuria in pregnant women can particularly cause problems for both mother and her fetus. Therefore in this study 950 pregnant women who have been referred to Tabriz university and private, gynaecology clinics for routine pregnancy cares, and had no sign s of UTI were s...
متن کاملAsymptomatic Urinary Tract Infection in Pregnant Women
Background and Objectives: Urinary tract infection is one of the most common bacterial infections in the human population, and more frequent infection during pregnancy. With notice to this point that most of urinary tract infections during pregnancy are asymptomatic, they could lead to serious complications such as prematurity, low-birth weight, hypertension, and higher fetal mortality rates if...
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